| Name | Meaning | Gender | Origin |
| Spence | Provider | M | English |
| Spencer | Administrator | E | English |
| Speranza | Hope | F | Italian |
| Spike | Long/ Heavy Nail | M | American |
| Spiro | Spiral | M | Greek |
| Sprague | Alert/ Lively | M | German |
| Spyridon | Round Basket | M | Greek |
| Stacey | Resurrection | F | Greek |
| Stacia | Resurrection | F | Slavic |
| Stacie | Resurrection | F | Greek |
| Stacy | Resurrection | E | English |
| Stan | From the name STANLEY | M | German |
| Stanislaus | Camp glory | M | Slavic |
| Stanislav | Glory of the Camp | M | Slavic |
| Stanislaw | From the name STANISLAV | M | Polish |
| Stanley | Rocky Meadow | M | German |
| Star | A Star | F | American |
| Starbuck | Astronaut | E | American |
| Starr | From the name STAR | F | American |
| Stash | Sun's rays | M | American |
| Stasia | Resurrection | F | Russian |
| Stavros | Crowned with Wreath | M | Greek |
| Stedman | From the Farmstead | M | English |
| Stefan | From the name STEVEN | M | German |
| Stefanie | Crowned One | F | Greek |
| Steffi | From the name STEVEN | F | American |
| Steffie | Nickname for STEPHANIE | F | American |
| Stella | Star | F | Italian |
| Step | From the name STEVEN | M | American |
| Stephan | Crowned One | M | Greek |
| Stephanie | From Stefanos - crown | F | Greek |
| Stephen | Crowned One | M | Greek |
| Sterling | Valuable | M | German |
| Stesha | Crowned One | M | Slavic |
| Steve | From the name STEVEN | M | Greek |
| Steven | Crowned One | M | Greek |
| Stevie | From the name STEVEN | E | American |
| Stew | From the name STUART | M | American |
| Stewart | From the name STUART | M | English |
| Stian | Swift | M | Scandinavian |
| Stillman | Quiet/ Gentle | M | English |
| Stockton | Town Near Tree Trunk | M | English |
| Stone | Stone | M | American |
| Storm | A Storm | E | American |
| Stormy | Impetuous Nature | E | American |
| Strom | Stream/ flow | M | German |
| Stu | Keeper of the Estate | M | English |
| Stuart | Keeper of the Estate | M | English |
| Studs | A House | M | American |
| Suchi | Radiant Glow | F | Hindi |